ABSTRACT

In his original series of studies on hypercortilism due to basophil adenomas, Cushing noted certain dermatological changes, and some patients had also sustained osteoporotic fractures 1 . Since the widespread application of long-term steroid therapy in clinical practice, skin- and bone-related complications in addition to many others are more frequently being encountered. This study was carried out to measure skin thickness and bone density changes in postmenopausal women taking long-term corticosteroids. Measurements were compared with those from a number of controls (postmenopausal females), patients who had sustained osteoporotic fractures and post-menopausal women on hormone replacement therapy.