ABSTRACT
Apoptosis is an essential process in embryonic development and tissue homeostasis, particularly in the prevention of disease. Written from a genetic viewpoint, Genetics of Apoptosis first describes the molecular and cell biology of apoptosis, then examines the process in more detail in several model systems. This volume brings together contributions from internationally renowned authors, and will be a valuable reference to all researchers studying apoptosis.
TABLE OF CONTENTS
chapter 1|4 pages
-Death receptors in apoptosis 27
7.3 Targeting death receptors for treatment of cancers
chapter 14|2 pages
Conclusion Acknowledgments
germ-cell apoptosis could also be explained by developmental checkpoints that lead to the demise of naturally occurring compromised germ cells. Similarly, sim ple alterations in the metabolism of germ cells could also lead to programmed cell death. Indeed, this hypothesis is supported by the fact that a large number of genetic loci lead to excessive germ-cell apoptosis (S. Milstein, Anton Gartner,
chapter 11|14 pages
Cell-culture systems In apoptosis
1. Introduction: advantages of cell culture to investigate apoptosis