ABSTRACT

Diabetes mellitus and cardiovascular (CV) disorders are closely intertwined. Adults with diabetes have rates of hypertension, dyslipidemia, heart disease, and stroke that are at least twice as high as those reported in adults without diabetes, whereas individuals with hypertension, obesity, and dyslipidemia have a greatly increased risk of subsequently developing diabetes and/or macrovascular disease. Like patients with CV disorders, adults (and children) with diabetes may also show evidence of brain dysfunction when evaluated with formal neuropsychological tests or with neurophysiological and neuroimaging measures.