ABSTRACT
In-vitro maturation (IVM) of immature oocytes retrieved from women without any ovarian stimulation is a promising new treatment especially for women with polycystic ovary syndrome (PCOS) and/or polycystic ovaries (PCO), with many successful pregnancies reported worldwide. Although Cha et al.1 reported the first birth using IVM of immature oocytes collected at cesarean section within an oocyte donation program in 1991, in 1994 it was Trounson and colleagues2 who put IVM into clinical practice when they reported the first pregnancy using a woman’s own immature oocytes collected by transvaginal ultrasound-guided follicle aspiration from a patient with polycystic ovaries.
