chapter  9
20 Pages

Spatial kinetics in immunological modeling

WithDaniel Coombs, Byron Goldstein

In this chapter, we will begin by describing chemical diffusion, and why it can be a useful approximation for objects that are not undergoing true Brownian motion (such as mobile T cells). We will then outline how diffusion-based modeling can be applied to model particular scenarios arising in cell- and tissue-scale immunology. We give a simple introduction to diffusion-limited reactions and demonstrate applications in immunology.