ABSTRACT

This chapter suggests metabolically controlled cell hydration as a biomarker for adequate estimation of biological effects of EMF on cells and organisms. The fact that there is a direct correlation between metabolic activity of cells and EMF sensitivity of cell hydration has also been shown by our previous study on age-dependent magnetic sensitivity of brain and heart muscle tissue hydration of rats. Both magnetized PS (MPS) and Non thermal (NT) micro wave (MW)-treated PS have modulation effect on cell hydration have been demonstrated on brain cortex and heart muscle tissues of rats in in vivo and in vitro experiments. Knowledge on the metabolic nature of the cellular sensor through which the EMF-treated water molecules and water dissociation products modulate cell metabolism seems extremely important for choosing an adequate biomarker for EMF dosimetry from the point of public health. It is known that, among a number of metabolic mechanisms involved in cell volume regulation, Na+/K+ pump has a central role.