ABSTRACT

Adenosine monophosphate-activated protein kinase (AMP-activated protein kinase, AMPK) has become an attractive target for the treatment of diseases, associated with metabolic disorders over the last decade. The therapeutic significance of the AMPK activation is evident in diabetes, obesity, metabolic syndrome, cardiovascular diseases, and even in cancer. AMPK activators of plant origin and their synthetic modifications are considered; presumed mechanisms of their action and therapeutic effects are noted in this chapter.