ABSTRACT
The majority of polyesters and polycarbonates are traditionally synthesized through conventional metal-based catalysis. One of the major advantages of enzyme catalysis is selectivity. The key feature of enzyme catalysis for the formation of telechelic structures is that the mild reaction conditions and selectivity allow for a large variety of different end groups to be incorporated without severe effects of side reactions. The degree of polymerization can easily be tailored to a desired size by adjusting the stoichiometry between the monomers/repeating units and the end cappers. The chemoselectivity of enzymes can be exemplified by the different reactions that each enzyme may catalyze. The chemoselectivity of enzymes can be exemplified by the different reactions that each enzyme may catalyze. Telechelic polyesters produced by enzyme-catalyzed polycondensation can result from two different end-capping strategies, either using a functional acid or a functional alcohol.
