ABSTRACT
This introduction presents an overview of the key concepts discussed in the subsequent chapters of this book. The book focuses on the genetic and genomic aspects of precision medicine (PM) for cancer. It explores a PM approach for treating lung cancer patients. The book describes PM for liver cancer. It relates how Circulating Tumor DNA (ctDNA) has been used for PM in cancer research and treatment. The book also describes the use of Circulating Tumor Cell (CTC) in breast cancer research and treatment. It reviews an "avatar" mouse model of human cancer. A fast and reliable human cancer avatar model would be very helpful for selecting the best treatment regimen for cancer patients. The book explains the major reason for drug resistance is an interaction between cancer and microenvironment. It describes a cellular personalized immunotherapy. The book discusses another PM treatment, hyperthermic intraperitoneal chemotherapy (HIPEC). It provides an overview and perspective for the PM treatment of hereditary cancer patients.
