ABSTRACT
42Poly (methyl methacrylate) is the most popular acrylic resin used in denture fabrication, owing to its inert and colour retention properties. Denture stomatitis is a common oral disease, which is associated with the adherence of micro-organisms (Candida albicans) to denture surfaces. It was noticed that the localization of C. albicans, associated with about 90% of denture stomatitis cases mainly observed in patients affected by AIDS/HIV, results in deterioration of the denture. This chapter aims to induce antifungal properties through surface-altered acrylic denture resin. To achieve this, cationic surfactant such as such as hexadecyl trimethyl ammonium bromide was blended with PMMA resin to fabricate denture having antifungal properties. The microbial analysis clearly illustrates the adequate repellence of C. albicans due to the hydrophobic nature of QAS in hot cured denture with optimum dose. The novelty of the work lies in the use of surfactant to obtain antifungal denture following an economic route along with substituting the dependence on drugs used in customary treatment against candidiasis disease that may impart adverse effects on health. The application of the suggested technique avoids such adverse effects and provides as a viable solution.
