ABSTRACT

Camila Hirotsu Department of Psychobiology, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925, Vila Clementino, São Paulo, 04024-002, Brazil

Sergio Tufik Department of Psychobiology, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925, Vila Clementino, São Paulo, 04024-002, Brazil

Monica Levy Andersen Department of Psychobiology, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925, Vila Clementino, São Paulo, 04024-002, Brazil

Corresponding author: Camila Hirotsu, E-mail: milahirotsu@gmail.com

ABSTRACT

Sleep complaints are common in the population and affect well-being, productivity, and physical and mental capacity of individuals. Recently, there has been also a reduction in sleep duration due to higher socioeconomic pressure and 24/7 style of urban centers. However, both sleep disorders and sleep restriction constitute risk factors for hypertension, obesity and diabetes. These comorbidities are known as important contributors of chronic kidney disease (CKD), which is characterized by progressive and irreversible loss of kidney

function. Patients with CKD often have sleep disorders such as obstructive sleep apnea, insomnia, and restless legs syndrome. Besides being related to poorer quality of life and develop early with the disease, sleep disturbances are being recognized as risk factors for increased morbidity and mortality in CKD patients. Moreover, recent findings point to a bidirectional relationship between sleep and kidney, as short sleep duration has been associated with significant reduction of renal function in the general population.