ABSTRACT

Biosensor is a self-contained integrated receptor transducer device, and consists of a biological recognition element in intimate contact or integrated with the transducer. Biosensor technology has been envisioned to play a significant analytical role in medicine, agriculture, food safety, bioprocessing, environmental, and industrial monitoring. However, bulky and complex bench-top instruments used for detection and signal processing restrict the commercialization of biosensor technology. This also affects long-term implementation of biosensor system in point-of-care clinical applications. Over the past decade, the integration of biosensors with miniaturized electronic circuits to develop hand-held biosensor devices has garnered considerable attention in the scientific community and industry. This chapter outlines some recent advances made in interfacing the biosensors with miniaturized electronic circuits to develop compact biosensor devices for point-of-care diagnosis.