ABSTRACT

Nanotechnology has played a significant role in the development of biosensing devices over the past few decade. The development, testing, optimization, and validation of new biosensors have become highly interdisciplinary efforts involving experts in chemistry, biology, physics, engineering, and medicine. Various types of nanomaterials are being utilized for the fabrication of biosensing electrode to monitor their respective response studies. Nanomaterials based electrochemical immunosensors amplify the sensitivity by facilitating greater loading of the larger sensing surface with biorecognition molecules as well as improving the electrochemical properties of the transducer. Nanomaterials have similar dimension and provide high surface area to loading of biomolecules like proteins , enzymes, antigens (Ags), antibodies (Abs) and DNA. In this chapter, we have discussed about recent progress in the fields of nanotechnology, nanomaterial-based immunosensors, and their applications in the field of clinical diagnostics.