ABSTRACT

This chapter presents a comprehensive collection of nanoporous materials that have been modified and applied as a nanocatalyst in the important classes of Multicomponent reactions (MCRs). The nanoporous catalysts, mesoporous silica materials (MSMs) are more diverse and apt to be modified and used in catalytic applications. In 2010, mesoporous SBA-15 was applied for production of silver nanoparticles supported on the surface of the SBA-15 catalyst in the A3-coupling reaction of aldehydes, amines, and terminal alkynes using glycol as a green solvent. It was prepared by in situ reduction of silver nitrate (AgNO3) using hexamethylenetetramine as reducing agent to form Ag@SBA-15. In 2013, the synthesis of a novel gold stabilized in SBA-15 functionalized with disulfides was reported as an efficient and recyclable nanocatalyst in the A3-coupling reaction. For the preparation of the catalyst, pure mesoporous SBA-15 was initially functionalized by 3-(aminopropyl)triethoxysilane (APTES), and then it underwent an amidation with amine groups and a disulfide-based compound to introduce disulfide within pore channels.