ABSTRACT
This chapter focuses on approaches to improving the accuracy of cardiac single-photon emission computerized tomography, Single-photon emission computed tomography (SPECT) quantification with the corporation of hybrid SPECT/ computed tomography (CT) systems. It also focuses on the photon attenuation, Compton scatter, resolution loss, and partial volume effects attributable to SPECT image degradation. Image restoration encompasses all efforts to correct for factors affecting the integrity of the original object under investigation. Compensation for attenuation presupposes information regarding the composition of the patient's body that a photon has to traverse. Compensation techniques for the degradation of SPECT resolution caused by the partial volume effects can be divided into three categories: image enhancement techniques, image-domain correction techniques employing anatomical knowledge, and projection-based techniques. Dynamic SPECT is an imaging procedure that uses radiotracers to obtain images that reflect fundamental biophysiologic functions of perfusion, metabolism, and neural integrity in body organs by quantifying the temporal changes of radionuclide concentrations.
