ABSTRACT

Physiological processes occurring in the human body are dynamic. Therefore, imaging techniques that have the ability to trace in vivo changing distributions of radiolabeled molecules can potentially provide important information about organ function, leading to more accurate diagnoses of various diseases with a positive impact on medical research. In particular, dynamic SPECT (dSPECT) studies that can measure temporal changes of three-dimensional (3D) radiotracer distributions can substantially increase the scope and capacity of nuclear medicine for a number of clinical applications.