ABSTRACT
Q1 Which of the following is not a characteristic of phase I clinical trials in paediatric oncology? A They are offered to patients for whom no known curative treatment
is available. B They assess whether a new agent is sufficiently efficacious to war-
rant further study. C Small numbers of patients are required. D They use a dose-escalating design. E They are conducted in large individual institutions or small consor-
tia of institutions.
