ABSTRACT
Polycystic ovary syndrome (PCOS) is the most common form of WHO 2 anovulation, characterized by a normo-gonadotrophic and normo-estrogenic hormonal pattern. In women who failed to ovulate following clomiphene citrate (CC resistant) or to conceive following CC treatment (CC failure), gonadotropins are usually the next line of treatment. As polycystic ovaries are extremely sensitive to gonadotropins, ovulation induction with exogenous gonadotropins carries a high risk for multiple follicle recruitment, ovarian hyper-stimulation syndrome (OHSS) and multiple pregnancies.
