chapter  44
Risk factors for Alzheimer’s disease
ByPatricia A. Boyle, Robert S. Wilson
Pages 6

Alzheimer’s disease (AD) is one of the top 10 leading causes of death for which there is no cure or disease modifying treatment, making it one of the most feared conditions of ageing (Alzheimer’s Association, 2015). By the time a clinical diagnosis of AD is made, the pathological hallmarks of the disease are widespread in the brain, making it very dicult to minimize damage and alter disease progression. Prevention of AD, therefore, ranks among the most signicant public health challenges of the twenty-rst century. Identication of risk factors for AD is important and will facilitate novel strategies to prevent or delay onset of disease.