ABSTRACT

Definitions 571 Clinical classification 572 Epidemiologic classification 573 Oliguric and nonoliguric acute kidney injury 573 Epidemiology 573 Prerenal azotemia and functional acute kidney injury 573 Intrinsic acute kidney injury 575 Postrenal acute kidney injury 581

Clinical manifestations of acute kidney injury 581 Prevention 587 Management 588 Prognosis and outcome 591 Acknowledgment 592 References 593 Review questions 597 Answer key 599

● Despite limitations of serum creatinine, the KDIGO AKI denition and staging should be used to guide clinical care.