ABSTRACT

Preeclampsia is a disease characterized by gestational hypertension and proteinuria that effects 2%– 8% of pregnancies worldwide [1]. In 2010, the rate of preeclampsia in the United States was 3.8%: an increase from 2.5% in 1987 [2]. This increase is disturbing since preeclampsia has a substantial impact on the intrauterine environment and is a leading cause of maternal and fetal mortality and morbidity [3,4]. It is well established that preeclampsia might have long-term consequences on the mother [5,6]. Regarding the offspring, previous studies have mainly addressed the increased risk of short-term outcomes such as cerebral palsy, encephalopathy, and febrile seizures [7]. This chapter will discuss what is currently known about the long-term morbidity associated with in utero exposure to preeclampsia.