ABSTRACT

Gestational trophoblastic diseases (GTD) are a number of related benign and malignant disorders characterized by trophoblastic proliferation. Complete (CHM) and partial (PHM) hydatidiform moles are benign gestational events that most oen resolve aer uterine evacuation. In a minority of patients, moles may persist or transform, resulting in malignant disease (gestational trophoblastic neoplasia [GTN]). Rarely, GTN may follow nonmolar gestations, including normal, aborted, or ectopic pregnancies. GTN comprises of invasive mole, choriocarcinoma, placental site trophoblastic tumor (PSTT), and epithelioid trophoblastic tumor (ETT), although most commonly the histology is unknown unless surgery is performed.