ABSTRACT
One key to mission success in extreme environments is the use of relevant knowledge to provide optimal performance. Knowledge provides the tools for the Artic explorer and the high-performance rescue team alike to survive and prosper in ice and snow or high seas. Knowledge comes in various forms. It may be possessed by experts in universities or research institutes. In the medical realm, there is a great deal of evidence that generative cultures are closely associated with a variety of good practices and outcomes. Good information flow is critical to the learning process. Use of appropriate knowledge is a key factor in mission success and human survival in extreme environments. One would think that in life-and-death situations like heart disease, people would not take chances. One would think that, when one is handling nuclear isotopes, people would check with engineers about potential hazards, but the technicians didn't do that in the Tokai-mura accident.
