This chapter considers the epistemological dilemmas inherent in conceptualizing anatomy as radical possibility and offers "the political anatomy of the body". It presents an analysis that situates anatomy and its post-humanist counterparts, assemblages, within the social relations of production and consumption of transnational capitalism. Petra Kuppers' radical conceptualization of disability as outlaw ontology deconstructs the sovereign subject and unhinges normative conceptions of the biological body/anatomy. However radical these possibilities may be, there remains a real danger in describing disabled bodies using such an extreme level of abstraction. Analogously, within the specific transnational conditions of colonialism, the becoming of black disabled bodies is likewise an intercorporeal phenomenon that foregrounds a violent hierarchical context largely ignored by contemporary theorists. Disability appears not just as physical variation nor as linguistic trope, but as the actual bloodied markings on the black body. When the imbrication of blackness and disability produces violent markings on enslaved bodies, the assault on these subjectivities is even more profound.