The relationship between digital humanities and decolonization has become a popular one, representing a range of interventions. These include decolonizing digital archives, addressing representation in digital knowledge production, and using digital media to create spaces for voices that go unheard in dominant narratives of literature, history, and culture. This chapter examines the complex politics of decolonization in digital humanities. It begins by considering how discourses of decolonization have been deployed in the context of digital humanities and situating them in postcolonial theory and science and technology studies. The chapter then explores digital humanities projects that participate in decolonizing knowledge production. In doing so, it makes the case for culturally located approaches to digital humanities that resist reinscribing the politics of colonialism.