Identification of miRNA-1 as a novel regulator of insulin-like growth factor-1 in deer antler proliferation and regeneration

In this study, we investigated whether IGF-1 is regu lated by miRNAs. MiRNA-1 was identified as participating in the growth of antler tissues and the restoration of miR-1 expression in deer antler cell reduced cell proliferation. Our results suggest that miR-1 is crucial in the proliferation of deer antler cells and has potential applications with regard to antler regeneration and growth.