ABSTRACT

A key goal in current cancer research is decoding the molecular mechanisms of tumour genesis, including how the tumour genome is affected by therapy. There are two main developments contributing to the dynamic in this field of research. First, new molecular techniques, such as high-throughput sequencing, make whole-genome analysis possible within increasingly shorter timeframes. Whereas the sequencing of the first human genome took seven years, today it can be done in just a few days, and it is expected that such sequencing will soon play a role in everyday clinical practice.