ABSTRACT

‘Que sera, sera – Whatever will be, will be – The future’s not ours to see,’ so we are told by the famous oldie sung by Doris Day in, ironically enough, the movie titled ‘The Man Who Knew Too Much’ (1956). What will life be like when we get old? Predictive genetic testing for late-onset diseases is an attempt to provide some partial answers to that unanswerable question. In cases of colorectal cancer ‘running in the family’, where an effective treatment exists, predictive genetic testing is recommended by medical experts even for minors (Duncan et al. 2008). However, with some late-onset diseases –such as Huntington’s–being untreatable, the availability of predictive testing has re-opened the discussion concerning ‘the right not to know’ (Erez et al. 2010).