ABSTRACT
schizotypy, is simply to posit a greater number of genetic risk factors increase the quantitative trait underlying risk. Although the risk for the development of schizophrenia increases with ever higher schizotypy values, the fully dimensional model suggests that there is no clear cut-off or distribution break, but a functional transition between high schizotypy and schizophrenia. Heritability studies suggest that the amount of variance explained through genetic effects is approximately 50 percent, although measures and their subscales do differ in this respect. The heritability studies as well as genetic association studies suggest that individual facets of schizotypy are moderated through different latent genetic factors that are likely to interact with one other. The genetic/biological core of schizotypy is likely to be the positive facet, which is biologically represented through the mechanism of aberrant salience. Finally, the chapter addresses author's personal view of the current situation regarding schizotypal genetic research, and to suggest possible directions for the future.
