ABSTRACT

Some of the poor water-soluble drug molecules are major problem for drug formulation practices. So, drug nanosuspensions are considered as an effective emerging solution which can be used for safe delivery of such kind of hydrophobic drugs. Scaling down of biocompatible nanoparticles or nanobiomaterials led to enhance drug aqueous solubility and bioavailability by increasing drug surface area when that comes into contact with biological media. Formulated nanosuspensions are stabilized by various polymers to get effective targeted delivery in cancer tissues and infarct zones with minimal damage to healthy tissues. So, the concept of preparation and application of nanosuspensions in this chapter is depicted in brief for highlighting their effective drug delivery designing and their administration routes, for example, parenteral, pulmonary, oral, and ocular which can be considered further for clinical and pharmaceutical purposes.