ABSTRACT

Involvement of the lungs, oro-pharynx, and lymph nodes is the more frequent clinical triad observed in paracoccidioidomycosis. A. Lutz described paracoccidioidomycosis for the first time and found the fungus in epithelioid granulomata of a submandibular lymph node. A. Carini and Splendore also called attention to lymph node involvement in cases with oro-pharyngeal lesions. Satellite lymph node involvement, as a component of the primary complex in paracoccidioidomycosis—the chancriform syndrome, is of rare occurrence, in contrast to what is seen in other infections such as syphilis, tuberculosis, and sporotrichosis. The lymph nodes are important in the development and maintainance of an adequate immune response. The clinical diagnosis of the lymph node involvement by P. brasiliensis can be suspected by their enlargement, softening, and fistulization, as well as by the coexistence of lesions in other sites, particularly in the oropharynx. Treatment of the lymphatic problem is the same as prescribed for other manifestations of the disease.