ABSTRACT
Lecithin cholesterol acyltransferase (LCAT) is one of the key enzymes in lipoprotein metabolism. It transfers fatty acids from 2-position of lecithin to unesterified cholesterol in nascent high density lipoprotein fraction. Apolipoprotein distribution and probably some aspects of lipoprotein metabolism are influenced by LCAT reaction. In the longitudinal training study where parameters of lipid metabolism were followed, changes in LCAT activity were measured. The training group consisted of healthy, normolipemic men selected randomly from the screening material of a local physical fitness research center. The training group exercised regularly for 15 weeks at least three times a week under the guidance of a physical educator. The controlled training was composed of aerobic exercises, such as jogging and cross-country skiing. Fasting blood samples were taken from the trainers once a week during the first training month and then once a month to the end of the test period.
