ABSTRACT

Various studies evaluated the effectiveness of programs targeting dementia risk factors for the primary prevention of dementia. Their unknown cost-effectiveness leaves policy makers in uncertainty for reimbursement decision making. We aimed to discuss methods to assess the cost-effectiveness of interventions targeted at the primary prevention of dementia. A literature review has identified the potential cost-effectiveness of hypothetical prevention interventions, which provided a valuable contribution to the discussion on how to deal with various methodological challenges. This evidence on potential health-economic effects could aid in the discussion on how to finance primary dementia prevention programs if they have been shown to be effective.