ABSTRACT
The presence of multiple surface functional groups, unique architectural design and monodispersity has rendered dendrimers suitable for various biomedical applications as polymeric carrier systems. Further, these unique properties also impart some intrinsic therapeutic activities into dendrimers, including anti-angiogenic, antibacterial, antiviral, anticancer, etc. Dendrimers have shown promising results in the controlled delivery of anti-infective agents. These have also shown promising anti-infective activity as epitomized by the marketed product of dendrimers which is currently in phase III clinical trial i.e. VivaGelTM. Polyanionic carbosilane dendrimers have also shown positive results for many researches exploring antiviral activity. This chapter presents an account on different types of dendrimers developed for antimicrobial activity, including dendrimer-based nanohybrids, and their propensity to be explored as anti-infective nanomedicines.
