ABSTRACT
SONAL SRIVASTAVA, JAYANT DEWANGAN, DIVYA TANDON, and SRIKANTA KUMAR RATH
CSIR-Central Drug Research Institute, Lucknow-226031, India, E-mail: skrath@cdri.res.in
Abstract .....................................................................................................528 15.1 Introduction ....................................................................................528 15.2 Evidence for Cancer Stem Cells ....................................................529 15.3 Models of Cancer Propagation .......................................................530 15.4 Cancer Stem Cell: An Overview ....................................................531 15.5 Normal Stem Cell versus Cancer Stem Cell ..................................532 15.6 The Microenvironment and the CSC Niche ...................................537 15.7 Self-Renewal Pathways of Cancer Stem Cells ..............................541 15.8 Therapy ..........................................................................................546 15.9 Future Perspectives ........................................................................549 15.10 Conclusion ....................................................................................550 15.11 Summary ........................................................................................550 Acknowledgments ....................................................................................551 Keywords ..................................................................................................551 References .................................................................................................551
ABSTRACT
