ABSTRACT
Abstract ................................................................................................. 482 16.1 Introduction ................................................................................ 482 16.2 Synthesis of Sucrose and Trehalose Alkyl Ethers ...................... 484 16.3 Self-Assembly Properties of Sucrose Alkyl Ethers
Under Aqueous Conditions ........................................................ 487 16.4 Self-Assembly Properties of Trehalose Alkyl Ethers
Under Aqueous Conditions ........................................................ 492 16.5 Conclusion ................................................................................. 495 Keywords .............................................................................................. 496 References ............................................................................................. 496
JUN-ICHI KADOKAWA*
Department of Chemistry, Biotechnology, and Chemical Engineering, Graduate School of Science and Engineering, Kagoshima University, 1-21-40 Korimoto, Kagoshima 890-0065, Japan
*E-mail: kadokawa@eng.kagoshima-u.ac.jp
ABSTRACT
In this chapter, the hierarchically organized self-assembly of sucrose and trehalose alkyl ether amphiphiles to construct nanoparticles and nanorods under aqueous conditions is described. Because amphiphiles contain antagonistic hydrophilic and hydrophobic moieties in the same molecule, their regularly organized self-assembly properties in water help in the formation of controlled aggregate morphologies. Carbohydrate-based amphiphiles composed of hydrophilic carbohydrate moieties and hydrophobic carbon chains have been extensively studied, and a large variety of self-assembly morphologies have been observed. As described in this chapter, the self-assembly properties of disaccharide alkyl ethers such as sucrose and trehalose derivatives have been investigated under aqueous conditions. These amphiphiles formed regularly organized nanoparticles and nanorods under aqueous conditions depending on their chemical structures. Their hierarchical self-assembly processes have been investigated using several analytical methods.
