ABSTRACT
The first reported technical success in human lung transplantation occurred in 1963 by James Hardy at the University of Mississippi. Following this report, it was apparent that results were extremely limited, with significant perioperative mortality. This did not change until 1983 when Joel Cooper and his team at Toronto General Hospital performed the first clinically successful lung transplant. This clinical success established lung transplantation as an effective treatment for patients with end-stage lung disease. Since that time, there has been tremendous progress with surgical techniques, donor organ preservation, organ perfusion techniques, and peri-and postoperative care.
