ABSTRACT

Diabetes Mellitus (DM) is a disease for which treatment is expensive, therefore many researchers are looking for a cheap and effective treatment. The aim of this study is to evaluate the effect of andaliman fruit extract to blood glucose level of mice with type 1 diabetes. The study was conducted on 25 male mice. The mice were divided into five groups. Every group was injected with alloxan intraperitoneally and treated with aquades, andaliman extract and metformin for 15 consecutive days. The results showed that administration of andaliman extract with doses of 100, 200 and 300 mg/kg decreased the blood glucose levels significantly compared to the negative control group (p < 0,05). Andaliman extract of 100 and 200 mg/kg were not significantly different from the positive control group (p > 0,05). Blood glucose levels of mice with DM type 1 were decreased after andaliman extract was administered.