Immunohistochemical Evaluation in Nasopharyngeal Carcinoma (Npc); Microvessel Density Expressions
To determine the expression of microvessel density in primary tumour size (T), lymph node (N) and clinical stage in nasopharyngeal carcinoma this descriptive study involved 30 samples in Haji Adam Malik General Hospital Medan. Nasopharyngeal carcinoma was mostly found in males (73.3%); 41-60 years old (60%); T4 primary tumour (36.7%), N3 lymph node (43.3%), and non-keratinising squamous cell carcinoma (53.3%). High microvessel density (>45 MV/LP) was found in 56.7%; non-keratinising squamous cell carcinoma (58.8%), T4 primary tumour (35.3%), N3 lymph node (47.1%); and stage 4 (76.4%). Microvessel density mostly overexpressed in non-keratinising squamous cell carcinoma, primary tumour size (T4), lymph node size (N3) and clinical stage 4.