Low survival rate in high-grade osteosarcoma: A retrospective study at a single institution in Indonesia
Osteosarcoma is a very rare malignant bone tumour, it is an aggressive bone neoplasm. Combination of surgical removal and systemic multidrug chemotherapy is the current treatment strategy. This study aims to evaluate the prognostic factors influencing the survival rate in our centre. A retrospective cohort study of patients diagnosed with osteosarcoma between January 2012 and December 2014 was carried out. A total of 58 osteosarcoma patients were included in this study, including 36 men (62%) and 22 women (38%), with a mean age at diagnosis of 15 years. The median survival of this group was 12 months. Patients with no pulmonary metastases after treatment had better survival rates of 18 and 90% at two years. The overall survival of osteosarcoma patients in this study is low. Patients who did not comply with treatment had a worse survival rate. Patients with pulmonary metastases have a significantly increased risk of death.