ABSTRACT
Nasal irrigation is the treatment of choice to relieve symptoms in chronic rhinosinusitis (CRS). Adding a surfactant to the solution may increase its efficacy, but the effects on mucociliary function are unknown. To determine the effect of nasal irrigation with surfactant on the symptoms and Mucociliary Transport Time (MTT) in CRS, 40 patients in the hypertonic saline and the baby shampoo group were evaluated for symptoms and MTT, before and after nasal irrigation, for two weeks. The difference of the average Sino- Nasal Outcome Test 20 (SNOT-20) score in the hypertonic group was statistically significant (p = 0.01), but not in the baby shampoo group. The average VAS score in both groups was significantly different (p = 0.01 and p = 0.05). Neither hypertonic nor baby shampoo solution affects MTT. Nasal irrigation with the baby shampoo solution has not affected the quality of life and MTT in CRS but may affect the severity of the disease.
