chapter  9
6 Pages

Effect of smoking on superoxide dismutase levels in DM with pulmonary TB patients

WithM.I. Sari, S.S. Widjaja, Z. Amir, D.M. Darlan, D.D. Wijaya

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Cigarette smoke contains free radicals. This condition can lead to the decrease of antioxidants. This study aims to determine the effect of cigarette smoking on Superoxide Dismutase Antioxidant (SOD) levels in Diabetes Mellitus (DM) with pulmonary Tuberculosis (TB) patients. The study was conducted on 30 male patients with DM with pulmonary TB. Smoking data was obtained by questionnaire. The SOD level was determined according to the ELISA technique. The mean values of SOD were analysed using SPSS software. There was no significant difference (p = 0.56) in the SOD levels of DM with pulmonary TB patients in non-smoker groups compared to those in smoker groups. The level of SOD had significant differences (p = 0.000) in smoker subjects by Brinkman index classification. Cigarette smoking can affect the SOD level in DM with pulmonary TB patients depending on the length of time a person has been smoking and the number of cigarettes per day that are smoked.