chapter  1
11 Pages

The Use of Ovarian Markers

WithNeena Malhotra, Siladitya Bhattacharya

Ovarian reserve is a term used to describe a woman's reproductive potential and is a reflection of her pool of primordial follicles or, more specifically, the number and quality of oocytes in her ovaries (1). Each woman is born with approximately 2 million primordial follicles, but this number drops to 400,000 around menarche as a consequence of follicular atresia (2). Follicle numbers fall further with age, and the rate of decline is faster when women are in their mid-30s. This decline in fertility potential is specific for an individual woman and is influenced by race as well as genetic and environmental factors.