ABSTRACT
The surface properties of an implantable biomaterial play an important role in biointegration and biocompatibility during a period starting with implantation and for the whole in-dwelling lifetime of the implant. Upon implantation, several biological events take place on the biointerface of material and tissue, which are mostly related with the surface properties of biomaterial. This chapter provides a brief outline about biomaterial surface phenomena and highlights the effects of surface properties upon biological reactions, particularly the immune response, that mostly occur on biomaterial interface.
