ABSTRACT

Abstract ................................................................................................... 26 2.1 Introduction .................................................................................... 26 2.2 Biological Characteristics .............................................................. 27 2.3 Epidemiology ................................................................................. 28 2.4 Diseases ......................................................................................... 30 2.5 Genomics ....................................................................................... 33 2.6 Pathogenesis ................................................................................... 37 2.7 Identification and Detection ........................................................... 38 2.8 Treatment and Prevention .............................................................. 41 2.9 Future Challenging ........................................................................ 43 Acknowledgments ................................................................................... 44 Keywords ................................................................................................ 44 References ............................................................................................... 44

LAN HU* and BAOGUANG LI

Division of Molecular Microbiology, OARSA, CFSAN, FDA, Laurel 20708, MD, USA

*Corresponding author. E-mail: lan16686@yahoo.com

ABSTRACT

Salmonella have been recognized as major foodborne pathogens and remain a tremendous medical and economic burden in the world. Salmonella enteric infections cause gastroenteritis, enteric fever, bacteremia, invasive nontyphoid Salmonella (NTS) disease, and asymptomatic carrier state. The most common serovars causing human and animal diseases are Salmonella typhi, Salmonella paratyphi, Salmonella enteriditis, Salmonella typhimurium, and Salmonella choleraesuis. It is important to understand the latest Salmonella epidemiological distribution, pathogenesis, genomics, and detection and identification methods. In this chapter, we will focus on the Salmonella epidemiology, genomics, molecular and biological detection methods, and the practical control measures.