ABSTRACT
Abstract ................................................................................................... 56 3.1 Introduction .................................................................................... 56 3.2 Biological Characteristics .............................................................. 57 3.3 Epidemiology ................................................................................. 59 3.4 Diseases ......................................................................................... 61 3.5 Genomics ....................................................................................... 64 3.6 Pathogenesis ................................................................................... 70 3.7 Identification and Detection ........................................................... 73 3.8 Treatment and Prevention .............................................................. 78 3.9 Advances in Campylobacter Research .......................................... 79 Keywords ................................................................................................ 81 References ............................................................................................... 82
LAN HU1* and DENNIS D. KOPECKO2
1Division of Molecular Microbiology, OARSA, CFSAN, FDA, Laurel 20708, MD, USA
2Combivax, LLC, Silver Spring 20906, MD, USA
*Corresponding author. E-mail: lan16686@yahoo.com
ABSTRACT
Campylobacter spp. are the leading cause of foodborne gastroenteritis in humans worldwide. Campylobacter can also trigger serious post-infectious sequelae such as reactive arthritis and Guillain-Barré syndrome. It is important to understand the latest Campylobacter epidemiology, pathogenesis, genomics, identification, and detection methods. This chapter will present an overview of the general concepts, mechanisms, new identification and detection methods. We will focus on Campylobacter jejuni and Campylobacter coli, which are the main causes of Campylobacter enteritis in humans, to improve food safety as well as public health.
