ABSTRACT

Osteomyelitis (OM) is a progressive infection of the bone marrow and cortex caused by Staphylococcus aureus. This leads to the inflammatory destruction of the bone and becomes difficult to treat. The standard duration of antibiotic treatment is 4–6 weeks. This study was designed to observe the utilization of antibiotics, including type, route, and duration of administration, as well as drug-related problems. The study was conducted retrospectively from 1 January 2010 to 31 December 2012 using the clinical and laboratories data of 40 patients (29 males and 11 females) with the age range of 13–64 years. The most widely used antibiotics were ceftriaxone (22 patients), cefazolin (17 patients), amikacin (14 patients), and gentamicin (13 patients). The most commonly used route of administration was the intravenous route (20 patients). The duration of therapy depended on the patient’s condition. Intravenous antibiotics were used for 2 weeks. Drug-related problems were drug interaction and adverse drug reactions.