ABSTRACT
The major purpose of this book has been to present an overall, systematic view of physiologic aging in humans and for comparison and elucidation, in experimental animals and cultured cell models. Given the increased incidence of disease associated with aging, a few diseases have been selected for brief discussion to serve as examples of (i) how pathology influences physiologic adjustments with advancing age and (ii) reciprocally, how old age and declining physiologic competence augment the susceptibility to disease and disability.
