ABSTRACT
Deep brain stimulation (DBS) has proven to be an effective surgical therapy
for patients with advanced Parkinson’s disease (PD) who continue to respond
to dopaminergic therapy, but face disabling complications such as dyskinesias
and motor fluctuations. Tremor, rigidity, bradykinesia, and levodopa-related
dyskinesia appear to be most responsive (1,2), whereas axial signs and symp-
toms, including postural instability, as well as speech and swallowing, are
more resistant to DBS.
