ABSTRACT

Skin cancer is the most common type of cancer in the United States. There are more than

one million new cases diagnosed each year (1). Basal cell carcinoma (BCC) accounts for

more than 75% of the total number of skin cancers and squamous cell carcinoma (SCC)

constitutes 15%. Although both skin cancers can be treated effectively with topical

medication, radiation, or surgery, unchecked growth of BCC and SCC can lead to local

destruction and functional impairment. Advanced stages of SCC can spread and

metastasize. Melanoma (MM) only constitutes 5% of the skin cancers but is more deadly.

Over the last few decades, the incidence of MM has been increasing steadily. In 2008, it is

estimated that there will be 62,480 newly diagnosed MMs, and 8420 deaths from this

cancer (1). Currently, there is no effective cure for advanced disease; only early diagnosis

followed by prompt excision ensures a good prognosis.